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Single-molecule view of coordination in a multi-functional DNA polymerase
Replication and repair of genomic DNA requires the actions of multiple enzymatic functions that must be coordinated in order to ensure efficient and accurate product formation. Here, we have used single-molecule FRET microscopy to investigate the physical basis of functional coordination in DNA poly...
Autores principales: | Pauszek, Raymond F, Lamichhane, Rajan, Rajkarnikar Singh, Arishma, Millar, David P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952088/ https://www.ncbi.nlm.nih.gov/pubmed/33704066 http://dx.doi.org/10.7554/eLife.62046 |
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