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Structural characterization of HIV-1 matrix mutants implicated in envelope incorporation

During the late phase of HIV-1 infection, viral Gag polyproteins are targeted to the plasma membrane (PM) for assembly. Gag localization at the PM is a prerequisite for the incorporation of the envelope protein (Env) into budding particles. Gag assembly and Env incorporation are mediated by the N-te...

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Detalles Bibliográficos
Autores principales: Eastep, Gunnar N., Ghanam, Ruba H., Green, Todd J., Saad, Jamil S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952133/
https://www.ncbi.nlm.nih.gov/pubmed/33485964
http://dx.doi.org/10.1016/j.jbc.2021.100321