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Farrerol Enhances Nrf2-Mediated Defense Mechanisms against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial Cells by Activating Akt and MAPK

Oxidative stress of the retinal pigment epithelium (RPE) is an essential element contributing to the progression of age-related macular degeneration (AMD). Notably, the activation of Nrf2 is regarded as an effective strategy for controlling oxidation. The novel 2,3-dihydroflavonoid compound farrerol...

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Detalles Bibliográficos
Autores principales: Ma, Ning, Yang, Xiaolin, Qi, Chong, Yu, Qinlei, Zhu, Chao, Ren, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952154/
https://www.ncbi.nlm.nih.gov/pubmed/33763175
http://dx.doi.org/10.1155/2021/8847844