Alantolactone suppresses the metastatic phenotype and induces the apoptosis of glioblastoma cells by targeting LIMK kinase activity and activating the cofilin/G-actin signaling cascade

Glioblastoma (GBM) is the most common aggressive brain tumor and is associated with an extremely poor prognosis, as the current standard of care treatments have limited efficacy. Natural compounds have attracted increasing attention as potential anticancer drugs. Alantolactone (ATL) is a natural sma...

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Detalles Bibliográficos
Autores principales: Wang, Xun, Zou, Shuang, Ren, Tong, Zhao, Li-Jun, Yu, Li-Fei, Li, Xiang-Yu, Yan, Xin, Zhang, Li-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952248/
https://www.ncbi.nlm.nih.gov/pubmed/33649781
http://dx.doi.org/10.3892/ijmm.2021.4901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952248/
https://www.ncbi.nlm.nih.gov/pubmed/33649781
http://dx.doi.org/10.3892/ijmm.2021.4901

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