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Can PIRCHE-II Matching Outmatch Traditional HLA Matching?

We analyzed in a cohort of 68,606 first deceased donor kidney transplantations reported to the Collaborative Transplant Study whether an epitope-based matching of donor-recipient pairs using the Predicted Indirectly ReCognizable HLA Epitopes algorithm (PIRCHE-II) is superior to currently applied HLA...

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Detalles Bibliográficos
Autores principales: Unterrainer, Christian, Döhler, Bernd, Niemann, Matthias, Lachmann, Nils, Süsal, Caner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952296/
https://www.ncbi.nlm.nih.gov/pubmed/33717167
http://dx.doi.org/10.3389/fimmu.2021.631246