In silico Analyses of Immune System Protein Interactome Network, Single-Cell RNA Sequencing of Human Tissues, and Artificial Neural Networks Reveal Potential Therapeutic Targets for Drug Repurposing Against COVID-19

Background: There is pressing urgency to identify therapeutic targets and drugs that allow treating COVID-19 patients effectively. Methods: We performed in silico analyses of immune system protein interactome network, single-cell RNA sequencing of human tissues, and artificial neural networks to rev...

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Detalles Bibliográficos
Autores principales: López-Cortés, Andrés, Guevara-Ramírez, Patricia, Kyriakidis, Nikolaos C., Barba-Ostria, Carlos, León Cáceres, Ángela, Guerrero, Santiago, Ortiz-Prado, Esteban, Munteanu, Cristian R., Tejera, Eduardo, Cevallos-Robalino, Doménica, Gómez-Jaramillo, Ana María, Simbaña-Rivera, Katherine, Granizo-Martínez, Adriana, Pérez-M, Gabriela, Moreno, Silvana, García-Cárdenas, Jennyfer M., Zambrano, Ana Karina, Pérez-Castillo, Yunierkis, Cabrera-Andrade, Alejandro, Puig San Andrés, Lourdes, Proaño-Castro, Carolina, Bautista, Jhommara, Quevedo, Andreina, Varela, Nelson, Quiñones, Luis Abel, Paz-y-Miño, César
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952300/
https://www.ncbi.nlm.nih.gov/pubmed/33716737
http://dx.doi.org/10.3389/fphar.2021.598925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952300/
https://www.ncbi.nlm.nih.gov/pubmed/33716737
http://dx.doi.org/10.3389/fphar.2021.598925

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