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Abatacept enhances blood regulatory B cells of rheumatoid arthritis patients to a level that associates with disease remittance

Abatacept, an inhibitor of CD28 mediated T-cell activation, has been shown to be effective in controlling inflammation during rheumatoid arthritis (RA). However, its effects on immune regulatory B and T cells (Bregs and Tregs) has not been fully explored. Thirty-one RA patients treated with abatacep...

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Detalles Bibliográficos
Autores principales: Alenazy, Maha Fahad, Saheb Sharif-Askari, Fatemeh, Omair, Mohammed A., El-Wetidy, Mohammad S., Omair, Maha A., Mitwalli, Hussam, Al-Muhsen, Saleh, Al-Masri, Abeer, Hamid, Qutayba, Halwani, Rabih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952390/
https://www.ncbi.nlm.nih.gov/pubmed/33707483
http://dx.doi.org/10.1038/s41598-021-83615-0