Elevated levels of mitochondrial CoQ(10) induce ROS-mediated apoptosis in pancreatic cancer

Reactive oxygen species (ROS) are implicated in triggering cell signalling events and pathways to promote and maintain tumorigenicity. Chemotherapy and radiation can induce ROS to elicit cell death allows for targeting ROS pathways for effective anti-cancer therapeutics. Coenzyme Q(10) is a critical...

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Detalles Bibliográficos
Autores principales: Dadali, Tulin, Diers, Anne R., Kazerounian, Shiva, Muthuswamy, Senthil K., Awate, Pallavi, Ng, Ryan, Mogre, Saie, Spencer, Carrie, Krumova, Katerina, Rockwell, Hannah E., McDaniel, Justice, Chen, Emily Y., Gao, Fei, Diedrich, Karl T., Vemulapalli, Vijetha, Rodrigues, Leonardo O., Akmaev, Viatcheslav R., Thapa, Khampaseuth, Hidalgo, Manuel, Bose, Arindam, Vishnudas, Vivek K., Moser, A. James, Granger, Elder, Kiebish, Michael A., Gesta, Stephane, Narain, Niven R., Sarangarajan, Rangaprasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952582/
https://www.ncbi.nlm.nih.gov/pubmed/33707480
http://dx.doi.org/10.1038/s41598-021-84852-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952582/
https://www.ncbi.nlm.nih.gov/pubmed/33707480
http://dx.doi.org/10.1038/s41598-021-84852-z

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