Cargando…

Anti-EGFR antibody 528 binds to domain III of EGFR at a site shifted from the cetuximab epitope

Antibodies have been widely used for cancer therapy owing to their ability to distinguish cancer cells by recognizing cancer-specific antigens. Epidermal growth factor receptor (EGFR) is a promising target for the cancer therapeutics, against which several antibody clones have been developed and bro...

Descripción completa

Detalles Bibliográficos
Autores principales: Makabe, Koki, Yokoyama, Takeshi, Uehara, Shiro, Uchikubo-Kamo, Tomomi, Shirouzu, Mikako, Kimura, Kouki, Tsumoto, Kouhei, Asano, Ryutaro, Tanaka, Yoshikazu, Kumagai, Izumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952593/
https://www.ncbi.nlm.nih.gov/pubmed/33707468
http://dx.doi.org/10.1038/s41598-021-84171-3