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Calcium calmodulin kinase II activity is required for cartilage homeostasis in osteoarthritis

WNT ligands can activate several signalling cascades of pivotal importance during development and regenerative processes. Their de-regulation has been associated with the onset of different diseases. Here we investigated the role of the WNT/Calcium Calmodulin Kinase II (CaMKII) pathway in osteoarthr...

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Detalles Bibliográficos
Autores principales: Nalesso, Giovanna, Thorup, Anne-Sophie, Eldridge, Suzanne Elizabeth, De Palma, Anna, Kaur, Amanpreet, Peddireddi, Kiran, Blighe, Kevin, Rana, Sharmila, Stott, Bryony, Vincent, Tonia Louise, Thomas, Bethan Lynne, Bertrand, Jessica, Sherwood, Joanna, Fioravanti, Antonella, Pitzalis, Costantino, Dell’Accio, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952598/
https://www.ncbi.nlm.nih.gov/pubmed/33707504
http://dx.doi.org/10.1038/s41598-021-82067-w