Joint profiling of DNA and proteins in single cells to dissect genotype-phenotype associations in leukemia

Studies of acute myeloid leukemia rely on DNA sequencing and immunophenotyping by flow cytometry as primary tools for disease characterization. However, leukemia tumor heterogeneity complicates integration of DNA variants and immunophenotypes from separate measurements. Here we introduce DAb-seq, a...

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Detalles Bibliográficos
Autores principales: Demaree, Benjamin, Delley, Cyrille L., Vasudevan, Harish N., Peretz, Cheryl A. C., Ruff, David, Smith, Catherine C., Abate, Adam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952600/
https://www.ncbi.nlm.nih.gov/pubmed/33707421
http://dx.doi.org/10.1038/s41467-021-21810-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952600/
https://www.ncbi.nlm.nih.gov/pubmed/33707421
http://dx.doi.org/10.1038/s41467-021-21810-3

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