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Joint profiling of DNA and proteins in single cells to dissect genotype-phenotype associations in leukemia
Studies of acute myeloid leukemia rely on DNA sequencing and immunophenotyping by flow cytometry as primary tools for disease characterization. However, leukemia tumor heterogeneity complicates integration of DNA variants and immunophenotypes from separate measurements. Here we introduce DAb-seq, a...
Autores principales: | Demaree, Benjamin, Delley, Cyrille L., Vasudevan, Harish N., Peretz, Cheryl A. C., Ruff, David, Smith, Catherine C., Abate, Adam R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952600/ https://www.ncbi.nlm.nih.gov/pubmed/33707421 http://dx.doi.org/10.1038/s41467-021-21810-3 |
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