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Influence of serum inflammatory cytokines on cytochrome P450 drug metabolising activity during breast cancer chemotherapy: a patient feasibility study

Individual response to chemotherapy in patients with breast cancer is variable. Obesity and exercise are associated with better and worse outcomes, respectively, and it is known that both impact the systemic cytokine milieu. Cytochrome P450 (CYP) enzymes are responsible for the metabolism of many ch...

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Detalles Bibliográficos
Autores principales: Crake, Rebekah L. I., Strother, Matthew R., Phillips, Elisabeth, Doogue, Matthew P., Zhang, Mei, Frampton, Chris M. A., Robinson, Bridget A., Currie, Margaret J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952716/
https://www.ncbi.nlm.nih.gov/pubmed/33707475
http://dx.doi.org/10.1038/s41598-021-85048-1