Exovesicular-Shh confers Imatinib resistance by upregulating Bcl2 expression in chronic myeloid leukemia with variant chromosomes

Chronic myeloid leukemia (CML) patients with complex chromosomal translocations as well as non-compliant CML patients often demonstrate short-lived responses and poor outcomes on the current therapeutic regimes using Imatinib and its variants. It has been derived so far that leukemic stem cells (LSC...

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Detalles Bibliográficos
Autores principales: Anusha, Dalal, Hamza, Subramanian, Sitalakshmi, V. P., Snijesh, Gowda, Divya A., H., Krishnamurthy, Damodar, Sharat, Vyas, Neha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952724/
https://www.ncbi.nlm.nih.gov/pubmed/33707419
http://dx.doi.org/10.1038/s41419-021-03542-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952724/
https://www.ncbi.nlm.nih.gov/pubmed/33707419
http://dx.doi.org/10.1038/s41419-021-03542-w

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