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Combining IL-10 and Oncolytic Adenovirus Demonstrates Enhanced Antitumor Efficacy Through CD8(+) T Cells

Oncolytic viruses are of growing importance in cancer therapeutics since they combine direct oncolytic effect and the stimulation of antitumor immunity. Emerging evidences showed that the function of oncolytic viruses is dependent on immune response in tumor microenvironment, and the modulation of i...

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Detalles Bibliográficos
Autores principales: Chen, Duo, Huang, Luyu, Zhou, Haiyu, Zhang, Yuhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952747/
https://www.ncbi.nlm.nih.gov/pubmed/33717103
http://dx.doi.org/10.3389/fimmu.2021.615089