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Dramatic intracranial response to tepotinib in a patient with lung adenocarcinoma harboring MET exon 14 skipping mutation

Mesenchymal‐epithelial transition (MET) pathway activation is associated with the mechanisms that influence properties affecting cancer cell survival and invasiveness. The MET exon 14 skipping mutation (METex14del) is found in 2%–3% of patients with non‐small cell lung cancer (NSCLC). Previous studi...

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Detalles Bibliográficos
Autores principales: Takamori, Shinkichi, Matsubara, Taichi, Fujishita, Takatoshi, Ito, Kensaku, Toyozawa, Ryo, Seto, Takashi, Yamaguchi, Masafumi, Okamoto, Tatsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952779/
https://www.ncbi.nlm.nih.gov/pubmed/33533182
http://dx.doi.org/10.1111/1759-7714.13871