Cargando…

Fatty acid-binding protein 4 silencing protects against lipopolysaccharide-induced cardiomyocyte hypertrophy and apoptosis by inhibiting the Toll-like receptor 4–nuclear factor-κB pathway

OBJECTIVE: To explore the effects and potential mechanisms of fatty acid-binding protein 4 (FABP4) in a lipopolysaccharide (LPS)-induced in vitro septic cardiomyopathy model. METHODS: Rat cardiomyocyte H9c2 cells were transfected with small interfering RNA (siRNA) against FABP4 (siFABP4), then induc...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Fangyuan, Chen, Gang, Yang, Yingyao, Lei, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952852/
https://www.ncbi.nlm.nih.gov/pubmed/33719658
http://dx.doi.org/10.1177/0300060521998233