Combined nicotinamide N-methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice

Obesity is a large and growing global health problem with few effective therapies. The present study investigated metabolic and physiological benefits of nicotinamide N-methyltransferase inhibitor (NNMTi) treatment combined with a lean diet substitution in diet-induced obese mice. NNMTi treatment co...

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Detalles Bibliográficos
Autores principales: Sampson, Catherine M., Dimet, Andrea L., Neelakantan, Harshini, Ogunseye, Kehinde O., Stevenson, Heather L., Hommel, Jonathan D., Watowich, Stanley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952898/
https://www.ncbi.nlm.nih.gov/pubmed/33707534
http://dx.doi.org/10.1038/s41598-021-85051-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952898/
https://www.ncbi.nlm.nih.gov/pubmed/33707534
http://dx.doi.org/10.1038/s41598-021-85051-6

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