Development of a potent embryonic chick lens model for studying congenital cataracts in vivo

Congenital cataracts are associated with gene mutations, yet the underlying mechanism remains largely unknown. Here we reported an embryonic chick lens model that closely recapitulates the process of cataract formation. We adopted dominant-negative site mutations that cause congenital cataracts, con...

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Detalles Bibliográficos
Autores principales: Li, Zhen, Gu, Sumin, Quan, Yumeng, Varadaraj, Kulandaiappan, Jiang, Jean X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952907/
https://www.ncbi.nlm.nih.gov/pubmed/33707565
http://dx.doi.org/10.1038/s42003-021-01849-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952907/
https://www.ncbi.nlm.nih.gov/pubmed/33707565
http://dx.doi.org/10.1038/s42003-021-01849-0

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