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Salivary dysbiosis in Sjögren’s syndrome and a commensal-mediated immunomodulatory effect of salivary gland epithelial cells

Salivary gland epithelial cells (SGECs) have been implicated in the pathogenesis of Sjögren’s syndrome due to aberrant antigen-presentation function. This study examined the hypothesis that oral dysbiosis modulates the antigen-presentation function of SGECs, which regulates CD4 T cell proliferation...

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Detalles Bibliográficos
Autores principales: Tseng, Yu-chao, Yang, Hsin-yi, Lin, Wei-ting, Chang, Chia-bin, Chien, Hsiu-chuan, Wang, Hon-pin, Chen, Chun-ming, Wang, Jann-tay, Li, Chin, Wu, Shu-fen, Hsieh, Song-chou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952914/
https://www.ncbi.nlm.nih.gov/pubmed/33707430
http://dx.doi.org/10.1038/s41522-021-00192-w