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Anticancer Properties of the Antipsychotic Drug Chlorpromazine and Its Synergism With Temozolomide in Restraining Human Glioblastoma Proliferation In Vitro

The extremely poor prognosis of patients affected by glioblastoma (GBM, grade IV glioma) prompts the search for new and more effective therapies. In this regard, drug repurposing or repositioning can represent a safe, swift, and inexpensive way to bring novel pharmacological approaches from bench to...

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Detalles Bibliográficos
Autores principales: Matteoni, Silvia, Matarrese, Paola, Ascione, Barbara, Buccarelli, Mariachiara, Ricci-Vitiani, Lucia, Pallini, Roberto, Villani, Veronica, Pace, Andrea, Paggi, Marco G., Abbruzzese, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952964/
https://www.ncbi.nlm.nih.gov/pubmed/33718225
http://dx.doi.org/10.3389/fonc.2021.635472