Nonsteroidal ecdysone receptor agonists use a water channel for binding to the ecdysone receptor complex EcR/USP

The ecdysone receptor (EcR) possesses the remarkable capacity to adapt structurally to different types of ligands. EcR binds ecdysteroids, including 20-hydroxyecdysone (20E), as well as nonsteroidal synthetic agonists such as insecticidal dibenzoylhydrazines (DBHs). Here, we report the crystal struc...

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Detalles Bibliográficos
Autores principales: Browning, Christopher, McEwen, Alastair G., Mori, Kotaro, Yokoi, Taiyo, Moras, Dino, Nakagawa, Yoshiaki, Billas, Isabelle M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pesticide Science Society of Japan 2021
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953031/
https://www.ncbi.nlm.nih.gov/pubmed/33746550
http://dx.doi.org/10.1584/jpestics.D20-095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953031/
https://www.ncbi.nlm.nih.gov/pubmed/33746550
http://dx.doi.org/10.1584/jpestics.D20-095

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