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Muscarinic inhibition of salivary glands with glycopyrronium bromide does not reduce the uptake of PSMA-ligands or radioiodine

RATIONALE: Salivary glands are highly perfused and express the prostate-specific membrane antigen (PSMA) receptor as well as the sodium—iodide symporter. As a consequence, treatment with (177)Lu/(225)Ac-PSMA for prostate cancer or (131)I for thyroid cancer leads to a high radiation dose in the saliv...

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Detalles Bibliográficos
Autores principales: Mohan, V., Bruin, N. M., Tesselaar, M. E. T., de Boer, J. P., Vegt, E., Hendrikx, J. J. M. A., Al-Mamgani, A., van de Kamer, J. B., Sonke, J.-J., Vogel, W. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953192/
https://www.ncbi.nlm.nih.gov/pubmed/33710423
http://dx.doi.org/10.1186/s13550-021-00770-1