An asymmetric junctional mechanoresponse coordinates mitotic rounding with epithelial integrity

Epithelia are continuously self-renewed, but how epithelial integrity is maintained during the morphological changes that cells undergo in mitosis is not well understood. Here, we show that as epithelial cells round up when they enter mitosis, they exert tensile forces on neighboring cells. We find...

Descripción completa

Detalles Bibliográficos
Autores principales: Monster, Jooske L., Donker, Lisa, Vliem, Marjolein J., Win, Zaw, Matthews, Helen K., Cheah, Joleen S., Yamada, Soichiro, de Rooij, Johan, Baum, Buzz, Gloerich, Martijn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953256/
https://www.ncbi.nlm.nih.gov/pubmed/33688935
http://dx.doi.org/10.1083/jcb.202001042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953256/
https://www.ncbi.nlm.nih.gov/pubmed/33688935
http://dx.doi.org/10.1083/jcb.202001042

Ejemplares similares