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An asymmetric junctional mechanoresponse coordinates mitotic rounding with epithelial integrity
Epithelia are continuously self-renewed, but how epithelial integrity is maintained during the morphological changes that cells undergo in mitosis is not well understood. Here, we show that as epithelial cells round up when they enter mitosis, they exert tensile forces on neighboring cells. We find...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953256/ https://www.ncbi.nlm.nih.gov/pubmed/33688935 http://dx.doi.org/10.1083/jcb.202001042 |