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Catalytic Asymmetric Synthesis of Unprotected β(2)-Amino Acids

[Image: see text] We report here a scalable, catalytic one-pot approach to enantiopure and unmodified β(2)-amino acids. A newly developed confined imidodiphosphorimidate (IDPi) catalyzes a broadly applicable reaction of diverse bis-silyl ketene acetals with a silylated aminomethyl ether, followed by...

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Detalles Bibliográficos
Autores principales: Zhu, Chendan, Mandrelli, Francesca, Zhou, Hui, Maji, Rajat, List, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953379/
https://www.ncbi.nlm.nih.gov/pubmed/33645969
http://dx.doi.org/10.1021/jacs.1c00249