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Breaking the barrier: an osmium photosensitizer with unprecedented hypoxic phototoxicity for real world photodynamic therapy

Hypoxia presents a two-fold challenge in the treatment of cancer, as low oxygen conditions induce biological changes that make malignant tissues simultaneously more aggressive and less susceptible to standard chemotherapy. This paper reports the first metal-based photosensitizer that approaches the...

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Detalles Bibliográficos
Autores principales: Roque, John A., Barrett, Patrick C., Cole, Houston D., Lifshits, Liubov M., Shi, Ge, Monro, Susan, von Dohlen, David, Kim, Susy, Russo, Nino, Deep, Gagan, Cameron, Colin G., Alberto, Marta E., McFarland, Sherri A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953430/
https://www.ncbi.nlm.nih.gov/pubmed/33738085
http://dx.doi.org/10.1039/d0sc03008b