Glycyrrhizin prevents SARS-CoV-2 S1 and Orf3a induced high mobility group box 1 (HMGB1) release and inhibits viral replication

Efforts to understand host factors critical for COVID-19 pathogenesis have identified high mobility group box 1 (HMGB1) to be crucial for regulating susceptibility to SARS-CoV-2. COVID-19 disease severity is correlated with heightened inflammatory responses, and HMGB1 is an important extracellular m...

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Detalles Bibliográficos
Autores principales: Gowda, Pruthvi, Patrick, Shruti, Joshi, Shanker Datt, Kumawat, Rajesh Kumar, Sen, Ellora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953444/
https://www.ncbi.nlm.nih.gov/pubmed/33773396
http://dx.doi.org/10.1016/j.cyto.2021.155496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953444/
https://www.ncbi.nlm.nih.gov/pubmed/33773396
http://dx.doi.org/10.1016/j.cyto.2021.155496

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