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SMIM1, carrier of the Vel blood group, is a tail-anchored transmembrane protein and readily forms homodimers in a cell-free system

Antibodies to the Vel blood group antigen can cause adverse hemolytic reactions unless Vel-negative blood units are transfused. Since the genetic background of Vel-negativity was discovered in 2013, DNA-based typing of the 17-bp deletion causing the phenotype has facilitated identification of Vel-ne...

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Detalles Bibliográficos
Autores principales: Nylander, Anja, Leznicki, Pawel, Vidovic, Karina, High, Stephen, Olsson, Martin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953501/
https://www.ncbi.nlm.nih.gov/pubmed/32301496
http://dx.doi.org/10.1042/BSR20200318