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An Experimental Study on [(125)I]I-pHLIP (Var7) for SPECT/CT Imaging of an MDA-MB-231 Triple-Negative Breast Cancer Mouse Model by Targeting the Tumor Microenvironment

OBJECTIVE: To evaluate the diagnostic efficacy of MDA-MB-231 triple-negative breast cancer with (125)I-labeled pHLIP (Var7) by single-photon emission computed tomography/computed tomography (SPECT/CT) imaging. METHODS: The binding fraction of [(125)I]I-pHLIP (Var7) and MDA-MB-231 cells was measured...

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Detalles Bibliográficos
Autores principales: Yu, Mingming, Sun, Yanqin, Yang, Guangjie, Wang, Zhenguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953584/
https://www.ncbi.nlm.nih.gov/pubmed/33746628
http://dx.doi.org/10.1155/2021/5565932