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Mettl14-mediated m6A modification modulates neuron apoptosis during the repair of spinal cord injury by regulating the transformation from pri‐mir‐375 to miR-375

BACKGROUND: Spinal cord injury (SCI) is a disabling disorder, resulting in neurological impairments. This study investigated the mechanism of methyltransferase-like 14 (Mettl14) on apoptosis of spinal cord neurons during SCI repair by mediating pri-microRNA (miR) dependent N6-methyladenosine (m6A) m...

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Detalles Bibliográficos
Autores principales: Wang, Haoyu, Yuan, Jing, Dang, Xiaoqian, Shi, Zhibin, Ban, Wenrui, Ma, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953660/
https://www.ncbi.nlm.nih.gov/pubmed/33706799
http://dx.doi.org/10.1186/s13578-020-00526-9