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Morusin induces osteogenic differentiation of bone marrow mesenchymal stem cells by canonical Wnt/β-catenin pathway and prevents bone loss in an ovariectomized rat model

BACKGROUND: Osteoporosis (OP) is a metabolic bone disease due to the imbalance of osteogenesis and bone resorption, in which, bone marrow mesenchymal stem cells (BMSCs) have a significant effect as the seed cells. Recent research has shown the function of Morusin on inhibiting osteoclast differentia...

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Detalles Bibliográficos
Autores principales: Chen, Ming, Han, Hui, Zhou, Siqi, Wen, Yinxian, Chen, Liaobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953707/
https://www.ncbi.nlm.nih.gov/pubmed/33712069
http://dx.doi.org/10.1186/s13287-021-02239-3