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Morusin induces osteogenic differentiation of bone marrow mesenchymal stem cells by canonical Wnt/β-catenin pathway and prevents bone loss in an ovariectomized rat model
BACKGROUND: Osteoporosis (OP) is a metabolic bone disease due to the imbalance of osteogenesis and bone resorption, in which, bone marrow mesenchymal stem cells (BMSCs) have a significant effect as the seed cells. Recent research has shown the function of Morusin on inhibiting osteoclast differentia...
Autores principales: | Chen, Ming, Han, Hui, Zhou, Siqi, Wen, Yinxian, Chen, Liaobin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953707/ https://www.ncbi.nlm.nih.gov/pubmed/33712069 http://dx.doi.org/10.1186/s13287-021-02239-3 |
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