The GM-CSF–IRF5 signaling axis in eosinophils promotes antitumor immunity through activation of type 1 T cell responses

The depletion of eosinophils represents an efficient strategy to alleviate allergic asthma, but the consequences of prolonged eosinophil deficiency for human health remain poorly understood. We show here that the ablation of eosinophils severely compromises antitumor immunity in syngeneic and geneti...

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Detalles Bibliográficos
Autores principales: Arnold, Isabelle C., Artola-Boran, Mariela, Gurtner, Alessandra, Bertram, Katrin, Bauer, Michael, Frangez, Ziva, Becher, Burkhard, Kopf, Manfred, Yousefi, Shida, Simon, Hans-Uwe, Tzankov, Alexandar, Müller, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953737/
https://www.ncbi.nlm.nih.gov/pubmed/32970801
http://dx.doi.org/10.1084/jem.20190706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953737/
https://www.ncbi.nlm.nih.gov/pubmed/32970801
http://dx.doi.org/10.1084/jem.20190706

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