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SOCS6 promotes radiosensitivity and decreases cancer cell stemness in esophageal squamous cell carcinoma by regulating c-Kit ubiquitylation

BACKGROUND: Radiotherapy is a major treatment for esophageal squamous cell carcinoma (ESCC). However, HPV infection related radioresistance caused poor prognosis of ESCC. The function of SOCS6, which has been shown to be a tumor suppressor in several cancers, has not been fully investigated up till...

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Detalles Bibliográficos
Autores principales: Sun, Xuanzi, Sun, Yuchen, Li, Jing, Zhao, Xu, Shi, Xiaobo, Gong, Tuotuo, Pan, Shupei, Zheng, Zhongqiang, Zhang, Xiaozhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953756/
https://www.ncbi.nlm.nih.gov/pubmed/33712005
http://dx.doi.org/10.1186/s12935-021-01859-2