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BG-flow, a new flow cytometry tool for G-quadruplex quantification in fixed cells

BACKGROUND: Nucleic acids can fold into non-canonical secondary structures named G-quadruplexes (G4s), which consist of guanine-rich sequences stacked into guanine tetrads stabilized by Hoogsteen hydrogen bonding, π-π interactions, and monovalent cations. G4 structure formation and properties are we...

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Detalles Bibliográficos
Autores principales: De Magis, Alessio, Kastl, Melanie, Brossart, Peter, Heine, Annkristin, Paeschke, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953821/
https://www.ncbi.nlm.nih.gov/pubmed/33706790
http://dx.doi.org/10.1186/s12915-021-00986-6