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Single-cell microfluidics facilitates the rapid quantification of antibiotic accumulation in Gram-negative bacteria

The double-membrane cell envelope of Gram-negative bacteria is a formidable barrier to intracellular antibiotic accumulation. A quantitative understanding of antibiotic transport in these cells is crucial for drug development, but this has proved elusive due to a dearth of suitable investigative tec...

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Detalles Bibliográficos
Autores principales: Cama, Jehangir, Voliotis, Margaritis, Metz, Jeremy, Smith, Ashley, Iannucci, Jari, Keyser, Ulrich F., Tsaneva-Atanasova, Krasimira, Pagliara, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953842/
https://www.ncbi.nlm.nih.gov/pubmed/32613221
http://dx.doi.org/10.1039/d0lc00242a