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Single-cell microfluidics facilitates the rapid quantification of antibiotic accumulation in Gram-negative bacteria
The double-membrane cell envelope of Gram-negative bacteria is a formidable barrier to intracellular antibiotic accumulation. A quantitative understanding of antibiotic transport in these cells is crucial for drug development, but this has proved elusive due to a dearth of suitable investigative tec...
Autores principales: | Cama, Jehangir, Voliotis, Margaritis, Metz, Jeremy, Smith, Ashley, Iannucci, Jari, Keyser, Ulrich F., Tsaneva-Atanasova, Krasimira, Pagliara, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953842/ https://www.ncbi.nlm.nih.gov/pubmed/32613221 http://dx.doi.org/10.1039/d0lc00242a |
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