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Glibenclamide, ATP and metformin increases the expression of human bile salt export pump ABCB11

Background: Bile salt export pump (BSEP/ABCB11) is important in the maintenance of the enterohepatic circulation of bile acids and drugs. Drugs such as rifampicin and glibenclamide inhibit BSEP. Progressive familial intrahepatic cholestasis type-2, a lethal pediatric disease, some forms of intrahepa...

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Detalles Bibliográficos
Autores principales: Vats, Nisha, Dubey, Ravi Chandra, Sanal, Madhusudana Girija, Taneja, Pankaj, Venugopal, Senthil Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953918/
https://www.ncbi.nlm.nih.gov/pubmed/33763207
http://dx.doi.org/10.12688/f1000research.26632.1