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P4HA1 Down-Regulation Inhibits Glioma Invasiveness by Promoting M1 Microglia Polarization
BACKGROUND: Polarization of microglia cells in the glioma microenvironment is closely related to the malignant progression and invasion of gliomas. Prolyl 4-hydroxylase subunit α1 (P4HA1) is the rate-limiting subunit of prolyl 4-hydroxylase (P4H). In previous studies, we showed that P4HA1 could prom...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954035/ https://www.ncbi.nlm.nih.gov/pubmed/33727827 http://dx.doi.org/10.2147/OTT.S299977 |