Cargando…
P4HA1 Down-Regulation Inhibits Glioma Invasiveness by Promoting M1 Microglia Polarization
BACKGROUND: Polarization of microglia cells in the glioma microenvironment is closely related to the malignant progression and invasion of gliomas. Prolyl 4-hydroxylase subunit α1 (P4HA1) is the rate-limiting subunit of prolyl 4-hydroxylase (P4H). In previous studies, we showed that P4HA1 could prom...
Autores principales: | Wang, Qiyan, Zhang, Junwen, Fang, Sheng, Wang, Jialin, Han, Xiangming, Liu, Fusheng, Jin, Guishan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954035/ https://www.ncbi.nlm.nih.gov/pubmed/33727827 http://dx.doi.org/10.2147/OTT.S299977 |
Ejemplares similares
-
P4HA1 Regulates CD31 via COL6A1 in the Transition of Glioblastoma Stem-Like Cells to Tumor Endothelioid Cells
por: Han, Xiangming, et al.
Publicado: (2022) -
Knockdown of P4HA1 inhibits neovascularization via targeting glioma stem cell-endothelial cell transdifferentiation and disrupting vascular basement membrane
por: Zhou, Yiqiang, et al.
Publicado: (2017) -
Recruitment mechanisms and therapeutic implications of tumor-associated macrophages in the glioma microenvironment
por: Zhou, Xianzhe, et al.
Publicado: (2023) -
Glioma-associated mesenchymal stem cells-mediated PD-L1 expression is attenuated by Ad5-Ki67/IL-15 in GBM treatment
por: Zhang, Qing, et al.
Publicado: (2022) -
AEG-1 silencing attenuates M2-polarization of glioma-associated microglia/macrophages and sensitizes glioma cells to temozolomide
por: Li, Jing, et al.
Publicado: (2021)