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[(18)F]-FDHT PET/CT as a tool for imaging androgen receptor expression in high-grade glioma
BACKGROUND: G lioblastoma (GBM) is associated with poor overall survival. Recently, we showed that androgen receptor (AR) protein is overexpressed in 56% of GBM specimens and AR antagonists induced dose-dependent death in several GBM cell lines and significantly reduced tumor growth and prolonged th...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954111/ https://www.ncbi.nlm.nih.gov/pubmed/33738450 http://dx.doi.org/10.1093/noajnl/vdab019 |