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Minimal role of interleukin 6 and toll-like receptor 2 and 4 in murine models of immune-mediated bone marrow failure

Immune aplastic anemia (AA) results from T cell attack on hematopoietic cells, resulting in bone marrow hypocellularity and pancytopenia. Animal models have been successfully developed to study pathophysiological mechanisms in AA. While we have systemically defined the critical components of the ada...

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Detalles Bibliográficos
Autores principales: Solorzano, Sabrina, Kim, Jisoo, Chen, Jichun, Feng, Xingmin, Young, Neal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954294/
https://www.ncbi.nlm.nih.gov/pubmed/33711076
http://dx.doi.org/10.1371/journal.pone.0248343