Mecamylamine inhibits seizure-like activity in CA1-CA3 hippocampus through antagonism to nicotinic receptors

Cholinergic modulation of hippocampal network function is implicated in multiple behavioral and cognitive states. Activation of nicotinic and muscarinic acetylcholine receptors affects neuronal excitability, synaptic transmission and rhythmic oscillations in the hippocampus. In this work, we studied...

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Detalles Bibliográficos
Autores principales: Zapukhliak, Olha, Netsyk, Olga, Romanov, Artur, Maximyuk, Oleksandr, Oz, Murat, Holmes, Gregory L., Krishtal, Oleg, Isaev, Dmytro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954330/
https://www.ncbi.nlm.nih.gov/pubmed/33711021
http://dx.doi.org/10.1371/journal.pone.0240074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954330/
https://www.ncbi.nlm.nih.gov/pubmed/33711021
http://dx.doi.org/10.1371/journal.pone.0240074

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