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The blood-brain barrier studied in vitro across species

The blood-brain barrier (BBB) is formed by brain capillary endothelial cells (BECs) supported by pericytes and astrocytes. The BBB maintains homeostasis and protects the brain against toxic substances circulating in the blood, meaning that only a few drugs can pass the BBB. Thus, for drug screening,...

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Detalles Bibliográficos
Autores principales: Thomsen, Maj Schneider, Humle, Nanna, Hede, Eva, Moos, Torben, Burkhart, Annette, Thomsen, Louiza Bohn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954348/
https://www.ncbi.nlm.nih.gov/pubmed/33711041
http://dx.doi.org/10.1371/journal.pone.0236770