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A novel multimeric IL15/IL15Rα-Fc complex to enhance cancer immunotherapy

The role of T cells in controlling human cancers is well known. Their success requires continued persistence in vivo and efficient trafficking to tumor sites, requirements shared by other effectors such as Natural Killer (NK) cells. To date, cytokine IL2 remains the only clinically approved cytokine...

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Detalles Bibliográficos
Autores principales: Xu, Hong, Buhtoiarov, Ilia N., Guo, Hongfen, Cheung, Nai-Kong V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954438/
https://www.ncbi.nlm.nih.gov/pubmed/33763293
http://dx.doi.org/10.1080/2162402X.2021.1893500