GIP mediates the incretin effect and glucose tolerance by dual actions on α cells and β cells

Glucose-dependent insulinotropic polypeptide (GIP) communicates nutrient intake from the gut to islets, enabling optimal levels of insulin secretion via the GIP receptor (GIPR) on β cells. The GIPR is also expressed in α cells, and GIP stimulates glucagon secretion; however, the role of this action...

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Detalles Bibliográficos
Autores principales: El, K., Gray, S. M., Capozzi, M. E., Knuth, E. R., Jin, E., Svendsen, B., Clifford, A., Brown, J. L., Encisco, S. E., Chazotte, B. M., Sloop, K. W., Nunez, D. J., Merrins, M. J., D’Alessio, D. A., Campbell, J. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954443/
https://www.ncbi.nlm.nih.gov/pubmed/33712466
http://dx.doi.org/10.1126/sciadv.abf1948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954443/
https://www.ncbi.nlm.nih.gov/pubmed/33712466
http://dx.doi.org/10.1126/sciadv.abf1948

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