Surface-directed engineering of tissue anisotropy in microphysiological models of musculoskeletal tissue

Here, we present an approach to model and adapt the mechanical regulation of morphogenesis that uses contractile cells as sculptors of engineered tissue anisotropy in vitro. Our method uses heterobifunctional cross-linkers to create mechanical boundary constraints that guide surface-directed sculpti...

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Detalles Bibliográficos
Autores principales: Mondrinos, Mark J., Alisafaei, Farid, Yi, Alex Y., Ahmadzadeh, Hossein, Lee, Insu, Blundell, Cassidy, Seo, Jeongyun, Osborn, Matthew, Jeon, Tae-Joon, Kim, Sun Min, Shenoy, Vivek B., Huh, Dongeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954445/
https://www.ncbi.nlm.nih.gov/pubmed/33712463
http://dx.doi.org/10.1126/sciadv.abe9446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954445/
https://www.ncbi.nlm.nih.gov/pubmed/33712463
http://dx.doi.org/10.1126/sciadv.abe9446

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