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Interplay between Pds5 and Rec8 in regulating chromosome axis length and crossover frequency

Meiotic chromosomes have a loop/axis architecture, with axis length determining crossover frequency. Meiosis-specific Pds5 depletion mutants have shorter chromosome axes and lower homologous chromosome pairing and recombination frequency. However, it is poorly understood how Pds5 coordinately regula...

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Detalles Bibliográficos
Autores principales: Song, Meihui, Zhai, Binyuan, Yang, Xiao, Tan, Taicong, Wang, Ying, Yang, Xuan, Tan, Yingjin, Chu, Tingting, Cao, Yanding, Song, Yulong, Wang, Shunxin, Zhang, Liangran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954452/
https://www.ncbi.nlm.nih.gov/pubmed/33712462
http://dx.doi.org/10.1126/sciadv.abe7920