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Latrophilin GPCR signaling mediates synapse formation

Neural circuit assembly in the brain requires precise establishment of synaptic connections, but the mechanisms of synapse assembly remain incompletely understood. Latrophilins are postsynaptic adhesion-GPCRs that engage in trans-synaptic complexes with presynaptic teneurins and FLRTs. In mouse CA1-...

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Detalles Bibliográficos
Autores principales: Sando, Richard, Südhof, Thomas C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954527/
https://www.ncbi.nlm.nih.gov/pubmed/33646123
http://dx.doi.org/10.7554/eLife.65717